Using cell-free DNA to profile the tumor microenvironment

LiquidCell Dx is building the first truly comprehensive cancer ecosystem profiling platform — from a simple blood draw

LiquidCell Dx
What We Do

LiquidCell Dx provides a complete picture of the tumor and its microenvironment in a cost-effective and scalable liquid biopsy. By measuring what existing diagnostics miss — the tumor microenvironment — we predict therapy response with unprecedented accuracy.

The Problem

Cancer is a spatial ecosystem, not just a tumor

Today's tumor profiling tools focus narrowly on the tumor itself — mutations, genomic profiles, individual biomarkers. But molecularly similar tumors behave very differently, and the reason lies outside the tumor cell.

Existing tools to profile this spatial ecosystem require invasive tissue biopsies or lack the resolution to capture its complexity. LiquidCell Dx looks at the whole cancer spatial ecosystem — not just the tumor — from a simple blood draw.

Same seed, restrictive ecosystem
limited growth

Same seed, permissive ecosystem
aggressive spread

Tumor microenvironment

The surrounding network of immune cells, stromal cells, vasculature, and signaling — shapes whether a therapy will work. It can block or enable treatment response across immunotherapy, ADCs, and targeted therapies.

LiquidCell Dx

From blood sample to biological insight

Proprietary integrated AI platform that decodes spatial ecosystem biology to guide treatment decisions and drug development.

Blood Draw

Blood draw vial with cfDNA markers

A non-invasive liquid biopsy captures signals from both the tumor and its surrounding microenvironment.

LiquidCell DxAI Platform

Our Detection AI maps signals to nine biologically interpretable states. Signals reflect hallmark features of the tumor microenvironment.

DNA signals mapped to nine Spatial Ecotypes
Learn More

High-resolution profiling of the tumor microenvironment with spatial ecotypes

Read Paper

Clinical Output

Patient samples are classified into Spatial Ecotypes and translated into a clear, clinically relevant report.

LiquidCell Dx tumor microenvironment report
Who We Are

Built by Leaders in Genomics, Oncology and AI

We are physician-scientists, computational biologists, and biotech operators with deep expertise across spatial transcriptomics, cell-free DNA biology, and cancer profiling and monitoring. Our founding science introduced the spatial ecotype framework and the methods that make it readable from blood. Together, we built LiquidCell Dx to bring spatial tumor microenvironment profiling and monitoring out of the research lab and into routine clinical practice.

Partnerships

Partner With Us

We're building the future of cancer diagnostics with clinical, pharmaceutical, and diagnostic partners.

Pharmaceutical

Clinical trial collaborations and companion diagnostic development

Clinical

Academic and clinical validation studies across tumor types

Profiling and Monitoring

Integration with existing genomic profiling workflows and laboratory infrastructure